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KMID : 1134220070270030004
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Hanyang Medical Reviews
2007 Volume.27 No. 3 p.4 ~ p.25
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Structural and Physio-chemical Properties of Helicobacter pylori
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Cho Myung-Je
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Abstract
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In 1983 when Marshall and Warren first reported the gastric pathogen H. pylori, microbiologists and gastroenterologists would not have predicted that this bacterium would have been shown to be one of the most common bacterial infection in
human and the ethiologic agent of the majority of gastrodoudenal disorders. Although there are many documents of the presence of a gastric pathogen in the stomach of human, few have paid attention to it due to difficulty in sampling
and bias for asceptic conditions of gastric juice. Now H. pylori is recognized as an etiological pathogen of gastroduodenal disorders including chronic gastritis, peptic ulcer, and gastric cancers. H. pylori colonizes, restricted to gastric mucosa resulting in pathogenic events for inflammatory responses. Bacterial components of H. pylori could contribute to its adherence, adaptation, and colonization to/in gastric mucosa of human, of which understaning might provide
insihgts for prevention, diagnosis, and treatment of H. pylori infection.
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KEYWORD
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Helicobacter pylori, Microbiological, Gastroduonenal diseases
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